LeSean McCoy was pretty much the entire offense for Buffalo last season. Most opponents will likely expect Shady to get the ball a lot. They aren't wrong, but you can take advantage of all the focus on McCoy for some game-changing results.
McCoy isn't quite as effective as in the past, but he remains a dynamic HB in Madden. With Chris Ivory, you have a great short-yardage power back option, but for all other scenarios, McCoy is your guy.
The Bills' top two pass catching options are WR Kelvin Benjamin and TE Charles Clay. Ratings-wise, these two are nearly identical with a slight Speed, Catching, and size advantage going to Benjamin. Both make excellent red zone targets.
The QB decision is going to depend on play style. A.J. McCarron is lower down the ladder in ratings. Josh Allen, though, is the strongest arm in the game with a 99 Throw Power, but average Accuracay ratings, at best. Allen has the big play potential, but expect erratic throws.
A quality pair of safeties protect against the deep attack. Micah Hyde with a 92 OVR and Jordan Poyer with an 88 OVR are Zone Coverage specialists.
Tre'Davious White is your top CB and is one of the fastest players on the defensive side with 91 Speed. He's fairly balanced in zone and man, so quite versatile in multiple defensive schemes.
The Bills defensive line is a bit better than their ratings reveal. Jerry Hughes, Kyle Williams, and Trent Murphy make up a solid front with decent moves to break through the line. Murphy has the highest Hit Power of any Bills player with an 80+OVR.